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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP2R5C
All Species:
38.48
Human Site:
Y375
Identified Species:
70.56
UniProt:
Q13362
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13362
NP_002710.2
524
61061
Y375
P
I
M
F
P
S
L
Y
R
N
S
K
T
H
W
Chimpanzee
Pan troglodytes
XP_510170
605
69813
A484
S
L
I
S
D
N
A
A
K
I
L
P
I
M
F
Rhesus Macaque
Macaca mulatta
XP_001112240
806
91497
Y657
P
I
M
F
P
S
L
Y
R
N
S
K
T
H
W
Dog
Lupus familis
XP_854560
524
61058
Y375
P
I
M
F
P
S
L
Y
R
N
S
K
T
H
W
Cat
Felis silvestris
Mouse
Mus musculus
Q60996
524
60806
Y375
P
I
M
F
P
S
L
Y
R
N
S
K
T
H
W
Rat
Rattus norvegicus
XP_001077680
524
60854
Y375
P
I
M
F
P
S
L
Y
R
N
S
K
T
H
W
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512520
524
61016
Y375
P
I
M
F
P
S
L
Y
R
N
S
K
T
H
W
Chicken
Gallus gallus
NP_001072950
524
61120
Y375
P
I
M
F
P
S
L
Y
R
N
S
K
T
H
W
Frog
Xenopus laevis
NP_001087638
506
58853
V374
V
I
E
P
S
E
F
V
K
V
M
E
P
L
F
Zebra Danio
Brachydanio rerio
NP_001038286
578
67245
Y428
P
I
M
F
P
S
L
Y
R
N
S
K
T
H
W
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_392477
724
84384
Y432
P
I
M
Y
P
A
F
Y
R
N
S
R
N
H
W
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q8LF36
492
56491
V358
F
L
N
E
L
E
E
V
L
E
A
T
Q
P
P
Baker's Yeast
Sacchar. cerevisiae
P38903
757
85316
Y624
P
I
I
F
P
A
L
Y
E
L
T
S
Q
L
E
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
77.5
63.5
97.5
N.A.
96.7
96.9
N.A.
94.2
94.8
80.9
79.2
N.A.
N.A.
54.4
N.A.
N.A.
Protein Similarity:
100
79.1
64.5
97.7
N.A.
97.7
97.5
N.A.
96.7
96.9
83.5
84.5
N.A.
N.A.
63.6
N.A.
N.A.
P-Site Identity:
100
0
100
100
N.A.
100
100
N.A.
100
100
6.6
100
N.A.
N.A.
66.6
N.A.
N.A.
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
100
100
26.6
100
N.A.
N.A.
86.6
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
48.2
35.6
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
63.3
46.7
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
40
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
13.3
60
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
16
8
8
0
0
8
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
8
8
0
16
8
0
8
8
0
8
0
0
8
% E
% Phe:
8
0
0
70
0
0
16
0
0
0
0
0
0
0
16
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
70
0
% H
% Ile:
0
85
16
0
0
0
0
0
0
8
0
0
8
0
0
% I
% Lys:
0
0
0
0
0
0
0
0
16
0
0
62
0
0
0
% K
% Leu:
0
16
0
0
8
0
70
0
8
8
8
0
0
16
0
% L
% Met:
0
0
70
0
0
0
0
0
0
0
8
0
0
8
0
% M
% Asn:
0
0
8
0
0
8
0
0
0
70
0
0
8
0
0
% N
% Pro:
77
0
0
8
77
0
0
0
0
0
0
8
8
8
8
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
16
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
70
0
0
8
0
0
0
% R
% Ser:
8
0
0
8
8
62
0
0
0
0
70
8
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
8
8
62
0
0
% T
% Val:
8
0
0
0
0
0
0
16
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
70
% W
% Tyr:
0
0
0
8
0
0
0
77
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _